Aloe vera gel allergy is occasionally encountered in clinical practice. If it is clear that it is caused by aloe vera gel, first of all, the aloe vera gel should be discontinued. Secondly, the treatment will be decided according to the specific symptoms and clinical manifestations of the allergy. If it is simply the appearance of erythema and papules, that is, the local area is very small, it can be cured by simply taking oral anti-allergy drugs or even simply applying topical hydrocortisone butyrate cream or dinaide cream, etc. However, if the redness is obvious, the area is relatively large, and even edema of the eyelids and lips appears, oral glucocorticoids, such as prednisone tablets as well as loratadine, can be taken if necessary. Also, pay attention to sun protection and skin moisturization. If oozing and blistering occur, you also need to take oral prednisone, and you can collapse herbal water with astringent effect, etc., with topical hormone creams, like hydrocortisone butyrate, etc. Therefore, aloe vera gel allergy should definitely be stopped first, and then treated symptomatically according to the clinical manifestations.