Staying up all night and being weak can be regulated by diet, life and medication. Stay up all night body weak for a long time due to stay up all night, will affect the rest of the body organs, such as depletion of kidney yin, will cause the five heart heat (two heart and two feet heart fever, and conscious heart and chest heat), lumbar and knee soreness, dizziness, tinnitus, and other symptoms of kidney yin; such as depletion of the positive qi, impede the normal operation of qi and blood, will cause weakness, yellowish color, less qi and lazy (lack of strength, don’t want to talk), and other symptoms of qi and blood deficiency. 1. Dietary regulation: balanced diet, reasonable combination of meat and vegetables, easy-to-digest soft food to ensure adequate nutrition. 2. Lifestyle management: Reasonable arrangement of work and rest time, do not stay up late, sleep time should be sufficient; do not overwork in daily life, appropriate exercise to enhance physical fitness. 3. Medication: (1) If there are symptoms of kidney yin deficiency, such as red tongue with little moss and fine pulse (the pulse becomes narrower and thinner, and the rate is faster), you can use medicines that nourish yin and tonify the kidney, such as Liufidihuang Pill, and note that you should avoid indigestible food during the period of using medicines. (2) If the body is weak with symptoms of insufficient qi and blood, pale tongue, white moss, weak pulse or thin and astringent pulse, you can use the oral solution to regulate qi and blood, and note that patients with colds and fever should not take it. After staying up late, if you need to use medication, you should apply it under the diagnosis of a Chinese medicine practitioner, and you should not use medication on your own to avoid causing adverse consequences.