What is the epidemiology and etiology of kidney cancer?

  Kidney cancer accounts for about 2%-3% of adult malignant tumors, and the incidence rate varies from country to country or region to region, with the incidence rate in developed countries being higher than that in developing countries. According to the National Cancer Prevention and Treatment Research Office and the Health Statistics Information Center of the Ministry of Health, the incidence and mortality of kidney cancer in pilot cities and counties in China from 1988 to 1997 showed that: 1. the incidence and mortality of kidney cancer are on the rise; 2. the ratio of men to women is about 2:1; 3. urban areas are higher than rural areas, and the highest difference between them is 43 times.  The age of onset can be seen in all age groups, with a high incidence at the age of 50-70.  The cause of kidney cancer is not known. Its incidence is related to smoking, obesity, long-term hemodialysis, long-term use of antipyretic and analgesic drugs, etc.; certain occupations such as oil, leather, asbestos and other industrial workers have high prevalence; a few kidney cancers are related to genetic factors, called hereditary kidney cancer or familial kidney cancer, which accounts for 4% of the total number of kidney cancers. Kidney cancer caused by non-genetic factors is called sporadic kidney cancer.