Autologous stem cell transplantation, also known as autologous hematopoietic stem cell transplantation, is a form of bone marrow transplantation that is often used clinically in the treatment of lymphoma and multiple myeloma. After autologous stem cell transplantation, the patient will have a severe myelosuppression period, which requires enhanced care, and the common care methods are: a. Oral care, the patient’s mouth is prone to stomatitis, tongue inflammation, etc., which requires regular mouth rinsing with mouthwash to maintain oral hygiene and reduce oral infection. Second, perianal care, after the patient urinates, stool, regular cleaning of the perineum, you can apply 1:5000 potassium permanganate tablets sitz bath, to reduce the possibility of perianal infection. Third, digestive tract care, after transplantation, all tableware should be disinfected at high temperature, and all food should be autoclaved before the patient can eat, so as to minimize the possibility of digestive tract infection.