There are various methods for the treatment of primary trigeminal neuralgia: a. Patients with short onset and mild symptoms should first consider pharmacological treatment. Second, when drug treatment is ineffective or effective but the dose is too high leading to obvious side effects, various nerve blocks as well as glycerol injection of semilunar ganglion and radiofrequency treatment can be considered. Third, if the above treatment is ineffective, trigeminal nerve sensory root amputation, stereotactic radiofrequency sensory root destruction, trigeminal nerve microvascular decompression, gamma knife treatment, etc. can be chosen. Trigeminal nerve microvascular decompression is a traditional surgery with very mature technology and is the most effective treatment method at present. Specifically, an incision is made behind the ear on the painful side to expose the root of the trigeminal nerve, and then the arachnoid adhesions and compressed vessels are released and isolated under the microscope to relieve the compression of the trigeminal nerve, and the effect of this method is over 90%. Gamma knife is the latest high-tech treatment method, after a strict preoperative evaluation, a certain dose of gamma-radiation is focused on the trigeminal nerve root to achieve the treatment effect. This treatment method started around the 1980s. A large number of cases have been reported with very few side effects and no risk of death, but its efficacy is slightly lower than that of traditional surgery. All of the above methods can be used as treatment options for patients with trigeminal neuralgia, but the specific treatment should be determined under the guidance of a physician and the final treatment plan should be determined on a case-by-case basis for each patient.