White spots on the lower legs, can consider the appearance of vitiligo, senile white spots or anemia nevus and other skin and mucous membrane diseases. 1. Vitiligo: it can develop at any age, and can be aggravated by exposure to sunlight, mental stress or fatigue, etc. It is an acquired pigment loss skin and mucous membrane disease, and it can occur in any part of the body, with single or generalized white patches, and the size of the lesions varies. 2. senile white spots: belong to senile degeneration phenomenon, mostly caused by other senile changes, such as senile hemangioma, senile warts, color spot boundary is distinctive, can be a pin head or bean size, white spots around the skin is slightly concave. 3. Anemic nevus: the developmental defects of vascular tissues as well as functional abnormalities, can occur in any part of the body, manifested as pale spots of different sizes, the skin around the white spots becomes red after rubbing, and the white spots remain unchanged. If you find that your skin has white spots of unknown cause, you should consult a regular medical institution in time, and standardize the treatment after a clear diagnosis.