Diabetic urinary microalbumin exceeding 500 μg/min is the first consideration for diabetic nephropathy, which often belongs to the clinical diabetic nephropathy stage and is a more serious condition. Diabetic nephropathy is characterized by the presence of microalbumin in the urine, which is one of the most common microvascular complications of diabetes, whether it is type 1 or type 2 diabetes. To delay the progression of diabetic nephropathy, the first need to control blood glucose, it is generally recommended that patients with type 1 and type 2 diabetes control fasting blood glucose level at about 4.4~7.0 mmol/L, non-fasting blood glucose target <10.0 mmol/L. Middle-aged and elderly patients can be appropriately relaxed. Secondly, blood pressure control also plays an important role in slowing down the progression of diabetic nephropathy, and it should be controlled at ≤130/80 mmHg. Angiotensin-converting enzyme inhibitors (ACEI)/angiotensin II receptor blockers (ARB) are the drugs of choice. Please visit the hospital if you find elevated microalbumin.