Down’s syndrome is a disease in which a child is born with a very special face, but with abnormal development of the brain, especially of the nervous system, which causes mental retardation, due to a chromosomal abnormality in the development of the fetus during pregnancy. Since the chromosome is an extra chromosome on the 21 chromosomes, regardless of any race (European, Asian, African), the fetus with this abnormality will have the same facial features, two hanging eyes, and the most important feature is the abnormal development of the nervous system. The most famous example, which you can learn about through public figures, is a conductor named Zhou Zhou in what we call the Disabled Artists Group, and you can learn something about this disease through him. Why do we need to conduct screening for this disease now? It is because the incidence of this disease in the general population is 1/800, and this disease is not detected in a timely manner through routine screening methods during pregnancy, such as B-type ultrasound, and there is no way that these routine screening methods can detect this disease, once the child is born without other serious comorbidities, he or she may survive until the age of 30-40 years old, which will bring very serious consequences to the family and even society. Very serious consequences for the family and even the society. Through a long period of medical practice and scientific development, we found that screening biochemical values, such as alpha-fetoprotein and beta-agent, in the mid-pregnancy, we found that these abnormalities can have a screening effect for diseases, so we collected and processed the pregnant woman’s age, body weight, pregnancy and childbirth histories, as well as the laboratory values of the laboratories that did this test with a software, and through the screening of these values and calculations, calculated that the pregnant woman who had this test showed Down’s syndrome. The screening and calculation of these values to calculate the risk of Down’s syndrome disease for this pregnant woman who has had this test tells you how much risk your child has of developing Down’s syndrome during this pregnancy. If the woman is not at high risk, and if she has a negative Down syndrome test, the risk is basically low, so there is no need for her to worry about this, so that it affects the course of her pregnancy. We know that if a mother is too anxious during pregnancy, it can affect the development of her child’s personality.