The clinical significance of high B-type natriuretic peptide mainly includes the diagnosis of heart failure, the judgment of left ventricular hypertrophy in hypertensive patients, the monitoring of ischemic injury after myocardial infarction and the judgment of prognosis, and the differential diagnosis of dyspnea.
1.Diagnosis of heart failure: B-type natriuretic peptide level is obviously elevated in patients with heart failure, regardless of whether they have symptoms or not, and increases proportionally with the severity of heart failure. Therefore, B-type natriuretic peptide can be used as an effective test for the early diagnosis of heart failure, and those with elevated levels can undergo further cardiac examination.
2. Determination of left ventricular hypertrophy in hypertensive patients: Plasma B-type natriuretic peptide level is significantly higher in hypertensive patients, especially those with ventricular hypertrophy, than in those with normal blood pressure, and the increase of BNP is related to the degree of myocardial hypertrophy but not to the degree of hypertension.
3. Monitoring and prognosis of ischemic injury after myocardial infarction: B-type natriuretic peptide is a simple, accurate and effective biochemical marker for predicting progressive ventricular remodeling after one month of myocardial infarction, and it can also be used as a reliable screening index for risk grading after myocardial infarction.
4. Differential diagnosis of dyspnea: It is not easy to distinguish obstructive pulmonary disease from dyspnea caused by heart failure, but B-type natriuretic peptide test can provide a valuable basis for differential diagnosis. B-type natriuretic peptide levels are markedly elevated in people with heart failure, while B-type natriuretic peptide is normal in people with airway obstruction.
When the B-type natriuretic peptide is high, it is recommended to go to the hospital in time, complete the relevant examinations according to the doctor’s instructions, and then follow the doctor’s instructions to standardize the treatment after the diagnosis is clear.