( 4 ), patients with chronic pancreatitis, chronic pancreatitis is now considered to be an important precancerous lesion in a small number of patients, especially chronic familial pancreatitis and chronic calcified pancreatitis; ( 5 ), intraductal papillary mucinous neoplasm is also a precancerous lesion; ( 6 ), patients with familial adenomatous polyposis; ( 7 ), benign lesions with major distal gastrectomy, especially those who are more than 20 years postoperative; ( 8 ), high risk factors for pancreatic cancer include long-term smoking, heavy alcohol consumption, and long-term exposure to harmful ( 8 ) , high risk factors for pancreatic cancer include long-term smoking, heavy alcohol consumption, and long-term exposure to harmful chemicals.