Precocious puberty in girls is categorized into peripheral and central, which requires general treatment, drug treatment and surgery. Peripheral precocious puberty in girls is mostly caused by taking estrogen-containing drugs, food or contacting estrogen-containing cosmetics, etc. For treatment, it is necessary to cut off the exogenous estrogen, such as stopping taking estrogen-containing drugs, avoiding hormone-containing food for children, and refraining from using hormone-containing cosmetics. Central may be caused by trauma, infection, tumor, etc. Commonly used treatment means to use gonadotropin-releasing hormone analogues to inhibit hormone secretion, so as to achieve therapeutic effects, such as treprostinil, leuprolide and so on. The medication should be prescribed by the doctor. However, if the precocious puberty is caused by intracranial tumors compressing the hypothalamus, then timely surgical treatment is needed. Girls with precocious puberty must go to the hospital in time to take the relevant examination, and cooperate with the doctor for treatment.