What can cause motor conduction bundle involvement?

Motor conduction tract involvement is one of the clinical manifestations caused by primary intraspinal tumors. When the cervical spinal cord is partially compressed, with the increase of tumor, the symptoms of spinal cord conduction bundle compression will gradually appear on the basis of the original symptoms, such as compression of spinal cord thalamus bundle, which may lead to hyperalgesia or disappearance of pain and temperature sensation below the contralateral side of the lesioned segment; compression of posterior bundle, which may lead to hyperalgesia of deep sensation; involvement of motor conduction bundle, which may lead to upper motor neuron paralysis in the limbs below the ipsilateral lesioned segment, and spinal cord hemisection syndrome is a specific symptom of intradural extramedullary tumor. The spinal cord hemisection syndrome is a specific symptom of extramedullary tumor. Because of the partial compression of the cervical spinal cord, as the tumor increases, the symptoms of spinal cord conduction bundle compression gradually appear on the basis of the original symptoms, such as compression of the thalamic tract of the spinal cord, which may produce hyperalgesia or loss of pain and temperature sensation below the contralateral lesion segment; compression of the posterior tract, which may produce hyperalgesia; and involvement of the motor conduction bundle. Factors affecting the pathological changes of spinal cord compression mainly include: 1. the site of tumor compression and the nature of neural tissue structure The tolerance of various spinal cord nerve tissues to pressure varies: for example, tumors first stimulate nerve roots and then cause damage; the tolerance of gray matter to tumor compression is greater than that of white matter; the cone bundle and nerve fibers conducting proprioceptive and tactile sensation in white matter are thicker (5 μm to 21 μm in diameter), and nociceptive fibers are thinner (less than 2 μm in diameter). The fine fibers are more tolerant than the coarse fibers after compression, and they recover faster when the compression is lifted. Generally speaking, at the beginning of compression, the nerve root is traction, the spinal cord is displaced, followed by compression and deformation, and finally the spinal cord is degenerated, which gradually causes the neurological dysfunction of the tissue. 2, the impact of tumor on the blood circulation of the spinal cord venous dilatation, stasis and edema occur after venous compression; arterial compression causes insufficient blood supply, hypoxia and nutritional disorders in the innervated area, causing degeneration and softening of the spinal cord, and finally causing spinal cord necrosis. In terms of tolerance to ischemia, the gray matter is larger than the white matter, and the fine nerve fibers are larger than the thick nerve fibers. Intraoperatively, the dorsal surface of the spinal cord has been reported to be blue, with enlarged trophoblastic arteries and significant absence of draining veins, but a few small trophoblastic arteries are visible microscopically. The duration of intravertebral tumors is usually more than 1 year. The shortest reported symptom was 17 days and the longest was 12 years. The average duration of intramedullary tumors was 11.6 months, and the average duration of extramedullary tumors was 19.2 months. The hardness of the tumor and its harm to the spinal cord Soft tumors, especially the slow-growing ones, give the spinal cord sufficient time to adjust its blood circulation, so that the development is slower, the symptoms are lighter, and the spinal cord function recovers faster and better after surgery. Hard tumors, even if they are small in size, are easily embedded in the spinal cord, and any spinal activity can cause contusion and gliosis in the spinal cord, and most of the postoperative recovery is not satisfactory. 4. The growth mode of tumor and its growth rate Some intramedullary tumors are mainly expansion growth, while some are mainly infiltrative growth. The latter causes more damage to the spinal cord. If the tumor grows slowly, even if the spinal cord is obviously compressed, the symptoms can be milder because the spinal cord still has the ability to compensate; on the contrary, tumors that grow faster, especially malignant tumors, are likely to cause acute complete transverse damage to the spinal cord and require emergency surgery to release the spinal cord compression, even if the delay of 1 to 2 hours will often cause serious consequences.