Itchy nipples can be caused by inflammation of the nipple, endocrine changes, wearing new underwear allergies and other reasons. 1. Inflammation of the nipple: the nipple is the opening of the mammary ducts, the secretion of the breast is discharged through the nipple, when the discharge of secretion is blocked, when there is bacterial invasion, it will lead to local infection, which will cause local infection, itching and discomfort. Try to pay attention to cleanliness and hygiene, and take oral penicillin drugs, such as methicillin and amoxicillin, as prescribed by the doctor. 2. Endocrine changes: adolescent girls and pregnant women due to changes in hormone secretion, mammary ducts and the development of mammary glands, mammary skin capillary expansion can also cause nipple itching. A small amount of glandular secretion around the areola, not timely cleaning, bacterial infection can also stimulate the nipple, causing itching. 3. Wearing new underwear allergy: due to wearing new underwear or eating special food, local allergies may also occur, and itching symptoms may also occur. It is accompanied by reddish color of the skin or the appearance of hives. Chlorpheniramine maleate tablets can be taken orally under the guidance of a doctor. Patients with itchy nipples should also consider other causes such as tumor factors, and should go to the hospital in time for relevant examinations to rule out diseases.