Migraines are usually characterized by throbbing, swelling pain on one side of the head, and most patients suffer from tension. The symptoms can be aggravated by mental stress and physical fatigue. Some people try medication to relieve their symptoms temporarily, and then rely on medication for a long time. Is it okay to take Cipro for migraine? What are the side effects of long-term use? Acute phase medication and preventive phase medication are the two common medication options for migraine. There are 2 ways to choose medications for the acute phase: 1. The stepwise method, which means that NSAIDs are preferred for each headache attack, and then migraine-specific treatment medications are used if treatment fails. 2.Tiered approach, based on the degree of headache, degree of functional impairment and previous response to medication, if it is a severe attack then use specific therapeutic medication, otherwise use NSAIDs class of medication. There are numerous types of drugs in the prophylactic phase, including beta-blockers, antiepileptics, antidepressants, calcium channel antagonists, NSAIDs, etc. These drugs are generally indicated for patients with frequent seizures, especially those with more than one seizure per week that interfere with normal life. Cipro is a western medicine and patients may get relief from symptoms when they take it initially. However, it is not very effective for patients with a long history of the disease. Long-term use may produce many side effects such as drowsiness, weakness and impairment of organ functions, etc. Patients are advised to take appropriate medications under the advice of professional doctors in accordance with their specific conditions. For intractable migraine, it has been proved that the effect of medication is not obvious, so it is suggested that patients can consider surgical treatment. Microvascular decompression is an effective technique to treat migraine in response to the principle of nerve compression by blood vessels.