Is amyloidosis dermatomyositis serious

Dermatomyositis without myopathy is generally more severe, and the combination of lung involvement, malignancy, older age of onset, and hormone resistance suggests a poorer prognosis. Dermatomyositis without myopathy is a special subtype of dermatomyositis that has the typical rash of dermatomyositis but lacks muscle involvement. Its pathogenesis is related to a variety of factors, including genetics, environmental factors, and immunity. Muscle-less dermatomyositis may present with edematous mauve patches on one or both upper eyelids and periorbital areas, slightly elevated purple, pink, or dark red papules on the extensor surfaces of the joints, arthralgias, Raynaud’s phenomenon, and other clinical manifestations. After glucocorticosteroids (such as methylprednisolone, etc.) and immunosuppressants (such as cyclosporine, tacrolimus, etc.) have been widely used, the prognosis of myasthenia gravis dermatomyositis has been significantly improved, but when the patient is combined with lung involvement, malignant tumors, the age of onset of the disease and hormone resistance, it suggests that the prognosis is poorer. Patients with non-myopathic dermatomyositis are advised to go to the rheumatology and immunology department of regular hospitals and follow the doctor’s instructions for standardized treatment, and do not use drugs on their own.