Systemic lupus erythematosus is primarily an autoimmune disease. The factors that lead to the development of SLE are mainly two major systems: 1. The body’s own genes. Some patients with lupus erythematosus have found genes in their bodies that cause lupus erythematosus, and genes play an important role in the pathogenesis of lupus erythematosus; 2. Environmental factors, most commonly ultraviolet light, can stimulate the skin of lupus erythematosus patients, and abnormal immune reactions can occur in the skin, which can trigger the dysfunction of the body’s autoimmune system, and the normal immune system becomes abnormal and starts to attack The normal immune system becomes abnormal and starts to attack the human skin, joints, muscles and internal organs, thus causing a series of clinical manifestations, such as weakness, hair loss, erythema, fever and proteinuria, hematuria, anemia, etc., in which several organs are injured; 3. Chemicals, infection by certain bacteria and viruses also play a very important role in the initiation of lupus erythematosus.