Men’s ligation may affect their sex life in the early stages, but not later. Infection and pain may occur early after ligation surgery in men, so early sexual life may be affected. After ligation, painful nodules can occur due to chronic inflammation of the ligation line, spermatogonial granulomas, neurofibromatous hyperplasia, and other conditions that can affect the quality of sexual life. Vasectomy in men can also lead to epididymal stasis, which can cause discomfort in early sex, so avoid sex for two weeks after the procedure. Over time, the incision heals completely and has no effect on sex later. Ligation for men is a permanent form of birth control that blocks the passage of sperm out of the body by cutting off both vas deferens so that they cannot enter the semen.