The normal value of 24-hour urine protein quantification should be less than 0.15g. If the test shows elevated urine protein quantification, it indicates kidney damage, and the causes can be divided into physiological and pathological. Physiological causes are commonly overeating, eating too much high-protein food, such as various kinds of meat, fish and shrimp, and also transient elevation of urine protein quantification after strenuous exercise, which requires checking 24-hour urine protein quantification, not overeating and avoiding strenuous exercise. The pathological causes are kidney damage in diabetic patients, as well as various types of nephritis, pyelonephritis, nephrotic syndrome. 24-hour urine protein quantification exceeds the normal value should be taken seriously, promptly find the cause, combined with other tests to confirm the diagnosis, and then early treatment.