The normal value of CA125 is less than 35 U/mL, and CA125 up to 37.5 is considered mildly elevated.CA125 up to 37.5 should be investigated for the cause of the disease, and follow up. 1. Detection of etiology: women need to check for ovarian disease, and if abnormalities are ruled out, further examination of the cervix, endometrium, pancreas, liver, etc.; men need to be more vigilant against lung cancer, liver cancer, gastrointestinal or pancreatic cancer, etc. Of course, some non-tumor diseases can also be detected. Of course, some non-tumor diseases can also cause transient elevation of CA125 level, such as pelvic inflammatory disease, endometriosis, chronic hepatitis, chronic pancreatitis and so on. 2. Review and follow up: If people with family history of malignant tumors have elevated CA125 levels, even if there are no signs and symptoms, they must be reviewed and followed up. They should review whether they have any bad life habits and apply effective health interventions, and follow the doctor’s instructions for review, and if they have multiple strong positives, they should undergo in-depth clinical examination for early detection and treatment. Elevated CA125 as a single indicator does not have diagnostic significance, and should be further examined under the guidance of a doctor to clarify the diagnosis before treatment.