Dialysis line thrombolysis is often performed using urokinase thrombolysis and is indicated for those with dialysis catheter malfunction.
Dialysis catheter malfunction is the inability to achieve adequate dialysis when the effective blood flow to the catheter is less than 200 ml/min or the blood pump flow is less than 200 ml/min, and the arterial pressure is less than -250 mmHg or the venous pressure is greater than 250 mmHg.
Inject 5000~10000IU/ml of urokinase into the catheter and keep it for 25~30min and then withdraw it, or keep it for 10min and then push 0.3ml of urokinase solution inward every 3~5min.Partial thrombosis can be used by intravenous drip method, i.e., 25~300,000IU of urokinase is continuously and slowly dripped from the catheter for 6~10h.
During the use of attention to monitoring coagulation function, when the fibrin is less than 1.5g / L should stop drip. Active bleeding and severe uncontrollable hypertension need to be excluded before use. Adverse effects of the drug include bleeding, nausea and vomiting.
Those who need thrombolysis for pipeline dysfunction are advised to communicate with the physician of the cardiovascular access group in dialysis to choose the appropriate thrombolysis method.