Anal pain, sleep in the morning up does not hurt daytime pain, may be related to hemorrhoids, anal fistula, anal fissure, tumor and other conditions. 1. hemorrhoids: the patient will appear in the anal area of the purplish-red bumps, with the increase of the bumps, there will be obvious redness and swelling pain, there may be intermittent pain phenomenon, may be related to the daytime activities of large stimulus friction, and so on. 2. anal fistula: anal fistula is due to perianal abscess is not timely control of the evolution of the main manifestations of the anus near the seepage, anal moisture, itching, and may be intermittent episodes, so the patient will feel the pain in the daytime, get up in the morning does not hurt. 3. Anal fissure: patients with anal fissure will have hot stinging pain in anus, especially during and after defecation, the stinging pain will be aggravated, and will be relieved at other times. 4. Tumor: if the patient has intestinal tumor or anal cancer, obvious pain will appear, which may also be accompanied by anal bleeding and other phenomena, the pain may be irregular or persistent. Considering that there are many causes, it is suggested that patients should go to the hospital in time and do relevant examination for clear diagnosis, so as to avoid delay and aggravation of the condition.