Acne is known as acne in medicine. Acne can be categorized into grade I~IV according to its severity, and is often treated with drugs such as retinoids, erythromycin and lincomycin. 1. Grade I (mild): only manifested as pimples, mainly using local topical drugs such as benzoyl peroxide gel for treatment. 2. Grade II (mild to moderate): manifested as acne and inflammatory papules, can be treated with topical retinoic acid drugs such as retinoic acid cream or gel for antibacterial treatment, and benzoyl peroxide gel can also be used. 3. Grade III (moderate): manifested as acne, inflammatory papules, pustules, requiring topical or oral antibiotics for treatment, such as erythromycin, lincomycin and clindamycin. 4. Grade IV (severe): manifested as acne, inflammatory papules, pustules, cystic scarring, etc. It can be treated with oral isotretinoin to reduce sebum secretion and control the formation of blackheads and acne, and at the same time can alleviate and inhibit cystic and polymerized acne. Intradermal steroid hormone injections, such as trimethoprim or compound betamethasone, can be used if necessary. Girls with acne if the symptoms are serious, it is recommended to consult a doctor in a timely manner, under the guidance of the doctor, do not self-medication.