This is the most effective and safest way to confirm the diagnosis of rheumatoid arthritis. There are also some symptoms and related tests that can be used for reference 1. Symptoms: symmetrical swelling and pain in multiple joints of the hands and feet; 2. Antibodies: positive early indicators such as CCP, AKA, APF, rheumatoid arthritis 33; 3. MRI, ultrasound examination with synovitis, bone marrow edema, etc. Is rheumatoid arthritis because of pain in the joints of the hands? This is not necessarily the case, joint pain does not necessarily mean arthritis, arthritis must be consistent with joint swelling, no swelling of joint pain is not true arthritis. For hand joint pain should be carefully distinguished: 1, distal and proximal interphalangeal joint pain – hand arthritis 2, wrist, metacarpal and proximal interphalangeal joint swelling and pain – rheumatoid arthritis 3, only distal interphalangeal joint swelling and pain with psoriasis – psoriatic arthritis -4, only joint pain and fear of cold water, fear of wind but not swelling – idiopathic arthralgia syndrome 5, female postpartum hand joint pain – postpartum rheumatism How to make a preliminary judgment whether they have rheumatoid arthritis? If the patient has multiple symmetrical joint swelling and pain in the small joints of the hands and feet for ≥ 6 weeks, taking painkillers is effective but recurrent after stopping them, rheumatoid arthritis should be considered, and it is best to visit the rheumatology department of a regular hospital for a clear diagnosis. Is morning stiffness of the hand joints a sign of rheumatoid arthritis? Although morning stiffness in the hands is an early symptom of rheumatoid arthritis and an indicator of its activity, not all morning stiffness symptoms appear to be rheumatoid arthritis. The time of morning stiffness is particularly important. When morning stiffness is more than 1 hour or even several hours, morning stiffness can be considered the possibility of rheumatoid arthritis, if the morning stiffness is less than 1 hour, and the elderly, consider osteoarthritis this disease, before and after menopause women with morning stiffness of the hand should first consider menopausal arthritis.