Bactrim can be applied topically to the scrotal skin, mainly for the treatment of skin gram-positive coccus infections, and also to inhibit fungal infections. The first thing to do is to keep the area clean and hygienic before treatment, you can do local cleaning, after cleaning to keep dry, and then apply the drug topically for treatment, it is recommended to follow the medical advice not to use blindly on your own. The topical application of Bactrim to skin infections generally does not produce obvious complications or sequelae, but if after 2-3 days of continuous treatment, the symptoms of the original disease are not relieved, it is recommended to go to the hospital to adjust the relevant treatment in a timely manner. During the treatment period, it is necessary to keep the external genitalia and scrotum clean and hygienic, to wash and ventilate them regularly, and to keep them dry at all times, so that the disease may recover sooner. During the treatment period, it is also necessary to regularly observe the improvement of the symptoms, regularly go to the hospital for a review, and further adjust the medication if necessary.