Adenosylmethionine Butanedisulfate Enteric-coated Tablets and Silymarin can be taken together. Adenosylmethionine butanedisulfonate enteric-coated tablets and silymarin generally do not have drug interactions, and both have hepatoprotective and choleretic effects, so at the same time with the above indications, it is possible to use the drug together. Adenosylmethionine butanedisulfonate enteric-coated tablets are suitable for the treatment of pre-cirrhosis and cirrhosis-induced intrahepatic cholestasis, or intrahepatic biliary deposition during pregnancy. It should be contraindicated in persons who are hypersensitive to the drug, in persons with genetic defects that affect the methionine cycle or cause homocystinuria or with hyperhomocysteinemia. Common adverse reactions include abdominal pain, diarrhea, nausea, debility, headache, and pruritus. Silymarin is a Chinese herbal medicine made from the dried mature fruits of Silybum marianum, family Asteraceae, with bitter taste and cool nature, it has the efficacy of clearing heat and removing toxins (removing heat and poisonous evils from the body), preserving the liver and inducing choleretic effects, and it is suitable to be used in the treatment of liver and gallbladder dampness-heat (dampness-heat evils deposited in the liver and gallbladder), dystocia (pain in the area of the dystocia and ribs), and jaundice. There is no specific contraindication for the use of this product. Specific use of the drug should be under the guidance of a specialist, not unauthorized use of drugs.