Elderly people with medical conditions can take furosemide and spironolactone for a long time under the guidance of a doctor. 1. Furosemide: belongs to the potassium excretion diuretic, after the use of which can increase the excretion of water, sodium, potassium, etc. It can also inhibit the activity of prostaglandinolytic enzyme, thus having the effect of dilating blood vessels. It is mainly used in the treatment of heart failure, liver cirrhosis, hypertension and other diseases. Usually the drug needs to pay attention to the monitoring of electrolytes in the process of taking, to avoid the occurrence of hypokalemia, and should be treated with potassium supplementation in time. Secondly, cardiac arrhythmia, nausea, vomiting and other discomforts may occur after the use of the drug, and it is forbidden for those who are allergic to the drug and sulfonamides. Pregnant and lactating women need to use the drug under the guidance of a doctor. 2. Spironolactone: belongs to the potassium-preserving diuretic drugs, which can inhibit the release of aldosterone and promote the excretion of water, and is mainly used in the treatment of chronic heart failure, hypertension, primary aldosteronism, hypokalemia and other diseases. Often the drug may cause hyperkalemia after administration, so electrolytes should be monitored and prompt symptomatic treatment should be carried out. It may also cause nausea, vomiting and other discomforts, so it is contraindicated in patients with hyperkalemia. And pregnant and lactating women need to use the drug under the guidance of the doctor. To summarize, taking furosemide and spironolactone for the elderly can be taken for a long time so as to treat hypertension, heart failure and other diseases. The specific medication regimen is recommended to be decided after a comprehensive assessment of the condition by a doctor.