Headache during pregnancy may be caused by physiological factors such as overexertion and mental tension, which do not require special treatment. If it is caused by pre-eclampsia, gestational hypertension and other diseases, medication and surgical treatment will be required as prescribed by the doctor. 1. Physiological factors: Usually, pregnant women with poor living habits, overwork or mental tension may lead to headaches during pregnancy, which generally do not require special treatment. Most of the pregnant women can relieve themselves after proper rest and improving their mood. 2. Pre-eclampsia: Usually, it is necessary to use nifedipine, nimodipine, labetalol and other antihypertensive drugs as prescribed by the doctor, and some of them can be injected intravenously with nitroglycerin and sodium nitroprusside. Treatment with antispasmodics such as magnesium sulfate or sedatives such as diazepam is also prescribed. If the condition continues to progress or fails to improve, termination of pregnancy may be necessary. 3. Hypertension in pregnancy: usually follow the doctor’s instructions to use methyldopa, nicardipine and other antihypertensive drugs, if there is mental tension, anxiety and other conditions, but also with the use of phenobarbital, clonazepam and other sedative treatment. If cerebral edema, renal insufficiency and other phenomena, also need to take furosemide, mannitol and other diuretics treatment. It is recommended that patients with headaches during pregnancy, first exclude physiological factors, if it is clear that the disease, but also need to actively cooperate with the doctor’s treatment, not blindly use their own medication, in order to avoid adverse effects.