There are many reasons for high and low blood pressure during menopause, most of which are related to changes in hormone levels, endocrine disorders, and vegetative nerve dysfunction. 1. Endocrine disorders: Menopausal women, due to the decrease of estrogen level, lead to endocrine disorders, which can also cause increased secretion of adrenaline, accelerated heart rate and unstable blood pressure. In this case, estrogen, such as estradiol, should be supplemented appropriately to stabilize blood pressure. 2. Phytoneurological dysfunction: Menopausal people often have bad mood, irritability, depression, anxiety or lack of sleep, resulting in unstable blood pressure, high and low, can be treated by regulating phytoneurological function, such as oral ghrelin, vitamin B1, etc., which can improve the symptoms and make the blood pressure stable. 3. Atherosclerosis: menopause is usually around 50 years old, this age has reached middle age, often due to abnormalities in blood lipids, blood glucose, blood pressure, resulting in atherosclerosis, causing unstable blood pressure, this situation needs to be adjusted from the lifestyle, low-salt and low-fat diets, appropriate physical exercise, and control the three highs. At the same time, under the guidance of the doctor’s medication, such as atorvastatin calcium tablets, nifedipine tablets, aspirin enteric-coated tablets and so on, to prevent cardiovascular and cerebrovascular diseases.