Thyroid crisis, generally due to patients suffering from more severe primary hyperthyroidism, is caused by inadequate preparation before surgery, poor control of hyperthyroidism during treatment, as well as more postoperative stimulation of thyroid tissue and stress reactions in patients, and its clinical manifestations and management are as follows: 1. Clinical manifestations: The main clinical manifestations of patients are high fever, rapid pulse rate, > 120 beats per minute. At the same time, there is a combination of serious neurological, circulatory and digestive system dysfunction, such as irritability, sweating, vomiting, unexplained diarrhea, and even delirium, etc. If not treated in a timely manner can develop into coma, deficiency, shock, and even death, with a high probability of death; 2. Treatment: timely endocrine specialist rescue; monitoring of vital signs; application of fortified cortisone, propylthiouracil, iodine The treatment should include: prompt endocrine specialist resuscitation; monitoring of vital signs; application of intensive cortisone, prothiouracil, iodine, etc., and symptomatic supportive treatment.