The large difference between the upper and lower blood pressure, that is, the increase in pulse pressure, may be elderly hypertension, may also be caused by other diseases, as follows: a. Elderly hypertension: clinically most common in the elderly hypertensive population, elderly hypertensive patients due to long-term hypertension, it will cause left ventricular hypertrophy, there is an increase in heart beat, will cause a significant increase in systolic blood pressure. Due to the aggravation of atherosclerosis, there will be a decrease in the elasticity of the walls of the large arteries, which will cause a decrease in diastolic pressure, which will cause an increase in pulse pressure. Second, other diseases: other causes of increased pulse pressure are aortic valve closure insufficiency, severe anemia, hyperthyroidism, and some congenital heart disease, or rheumatic heart disease, syphilitic heart disease, infective endocarditis and other conditions.