Supplementation of vitamin B2 preparations in the case of confirmed vitamin B2 deficiency. There are various precautions when taking vitamin B2 according to different situations. There are no six contraindications to taking vitamin B2, and what needs to be focused on is the time of taking, daily diet, and drug compatibility. When taking vitamin B2, there are several conditions that need attention: First, the time of taking: vitamin B2 is a water-soluble vitamin, so it is not recommended to take it on an empty stomach before meals. It is recommended to take it after meals or with meals. Daily diet: 1. Avoid drinking alcohol: alcohol can affect the digestion and absorption of vitamin B2 by the intestinal mucosa, so alcohol should be avoided when taking vitamin B2; 2. Avoid raw eggs: there is a substance called ovalbumin in the protein of raw eggs, which can affect the absorption of vitamin B2 when combined with biotin; 3. Avoid coffee, strong tea and other drinks: these two drinks contain caffeine, which can stimulate Caffeine can stimulate adrenaline secretion, which will consume the existing vitamin B2 in the body; 4, eat less high-fiber food: high-fiber food will promote gastrointestinal peristalsis, which may reduce the body’s absorption of vitamin B2. Such as oats, yams, apples, dragon fruit, green beans, peas, etc. Third, drug pairing: 1, avoid taking with contraceptives, such as compound norethindrone tablets, compound methandienone tablets, etc. The ingredients in the contraceptive will interfere with the body’s absorption of vitamin B2; 2, avoid taking with anticoagulant drugs, such as aspirin, Bolivar, etc.. Anticoagulant drugs will be hydrolyzed in the stomach to generate sodium salicylate, which will change the pH of gastric juice when taken with vitamin B2 and increase the irritation of gastric mucosa; 3. Avoid taking with alkaline drugs, such as soda tablets, sodium bicarbonate tablets, etc. Vitamin B2 becomes very unstable when used with such alkaline drugs, which can easily dissolve and reduce the effectiveness of the drug. 4. Avoid taking it with Chinese herbal formulas containing tanning agents, which can affect the digestion and absorption of vitamin B2, such as Qilisan, cold and flu, Longchuan powder, etc. Other: 1. Vitamin B2 for children should be used under the guidance of a doctor; 2. When used with medicinal value charcoal, the interval between the two drugs should be 2-3 hours to prevent the effect of the medicine, and the overdose should not be taken, and it is recommended that the medicine be used according to the doctor’s prescription, and it should be used with caution by allergic persons.