Pemphigus vulgaris may be related to genetic, autoimmune, neuropsychiatric and other factors, general treatment, drug therapy and other treatments can be used, need to comply with medical advice. 1. General treatment: including removing the cause of the disease, such as actively treating the original or suspected cause of the disease, common diseases such as thyroid disease, depression, infection, etc.; adjusting the mental state, keep the spirit of relaxation, emotional well-being, to avoid anxiety, depression, etc.; can also cover the bald parts, such as changing the hairstyle, wearing a wig, hair pieces, hats, etc., to reduce the psychological burden. 2. Drug treatment: including local medication commonly used drugs such as halometasone, clobetasol propionate, etc. Local medication may appear folliculitis, skin atrophy and other adverse reactions. Minoxidil can also be used externally to improve the microenvironment of hair growth and promote hair growth. Systemic medication commonly used drugs include compound glycyrrhizin, corticosteroids and antihistamines, to pay attention to the adverse effects of drugs, such as weight gain, elevated blood pressure and so on. 3. Other treatments: mainly include photodynamic therapy, ultraviolet irradiation, fractional carbon dioxide laser and other physical treatments, which may have a certain therapeutic effect on pemphigus vulgaris. It is recommended that patients with pemphigus vulgaris should go to the hospital in time to find out the cause of the disease and make a clear diagnosis, so as not to delay the condition.