Repeated H. pylori infections may be caused by bacteria that develop drug resistance, failure to take medication as prescribed by the doctor, and not paying attention to diet and hygiene. 1. Bacterial resistance: In recent years, the resistance of H. pylori to antibiotics such as clindamycin has increased significantly, and the body’s immunity has declined, making it difficult to cure, and easy to get infected again and again. 2. Failure to comply with the doctor’s instructions to take medication: the eradication of Helicobacter pylori is generally selected quadruple therapy that is a proton pump inhibitor such as omeprazole + a bismuth such as bismuth pectin + two antibiotics such as amoxicillin, clarithromycin. If the patient misses the medication, does not take the medication on time and in accordance with the amount of medication, use enough treatment, can not cure H. pylori. If the first treatment is not complete, the second treatment is generally difficult to achieve satisfactory results, easy to repeat the infection. 3. Do not pay attention to dietary hygiene: often eat out is easy to re-infection of Helicobacter pylori. You can avoid re-infection by bringing your own utensils and using communal chopsticks. In addition, it is important to note that if one member of the family is infected with H. pylori, the others should also go to the hospital for screening of H. pylori. If it causes transmission within the family, it is very easy to be infected with H. pylori repeatedly. If necessary, meal sharing can be adopted and tableware should be carefully sterilized. When H. pylori infection occurs, you should go to the hospital in time and take appropriate treatment under the guidance of the doctor.