Children with enlarged lymph nodes may be caused by upper respiratory tract infections, rubella, Kawasaki disease and other diseases, and patients can be relieved by general treatment and medication. 1. Upper respiratory tract infection: patients should pay attention to rest, drink more water, maintain indoor air circulation, prevent cold, fever symptoms, can be through the application of fever-reducing patches, warm water baths and other ways to lower the temperature. Patients can take antipyretic and analgesic drugs, such as acetaminophen, ibuprofen, etc.; antibiotic drugs, such as amoxicillin, ampicillin, etc. under the guidance of the doctor for treatment. 2. Rubella: patients should pay attention to rest, increase the amount of water, if there is a high fever can be treated with acetaminophen, ibuprofen, etc. under the guidance of a doctor. 3. Kawasaki disease: patients should pay attention to the oral cavity and skin mucous membrane cleaning care, to avoid infection, can be under the guidance of the doctor to use aspirin, gammaglobulin, dipyridamole and other drugs for treatment. In addition, chronic granulocytic leukemia, measles, tuberculosis, etc. may also cause lymph node enlargement, it is recommended that patients seek medical examination in a timely manner to clarify the cause of the disease for targeted treatment.