The most obvious early manifestations of vitamin B1 deficiency are anorexia, dyspepsia and generalized malaise, paralysis and pins and needles in the legs, and continued progression of the disease can present obvious symptoms of dry or wet foot fungus. Vitamin B1 deficiency is also known as beriberi. The human body can not synthesize its own vitamin B1, most of the need to obtain from food, mainly from cereals, nuts, eggs and animal offal, if the diet for a long time to eat too fine processing of rice, noodles, or excessive dieting can cause vitamin B1 deficiency. Vitamin B1 deficiency can be anorexia in the early stage, manifested as dyspepsia, generalized fatigue, leg weakness, as well as pins and needles sensation, the disease continues to progress, can present ascending symmetrical peripheral neuritis, sensory and motor disorders, decreased muscle strength, vagus nerve damage and other symptoms of dry pediculosis. If the condition is dominated by wet pediculosis symptoms, right heart failure symptoms such as fatigue, palpitations, and shortness of breath may be present. The treatment of vitamin B1 deficiency is based on extragastrointestinal thiamine (vitamin B1, anti-foot fungus factor) in the acute stage, and oral thiamine is given after the condition is relieved. Usual diet life pay attention to more intake of vitamin B1 rich in high protein food, low salt diet, usually can supplement small doses of vitamin B complex.