There is no absolute clinical exclusion of rabies. After being bitten or scratched by an animal such as a cat or dog, the first step should be to clean and disinfect the wound, and promptly receive rabies vaccination and, if necessary, rabies vaccine immunoglobulin. However, according to the “Third Report of the Expert Consultation on Rabies” published by the World Health Organization, the “Ten-Day Observation Method” can help rule out rabies infection after an animal injury and whether vaccination can be stopped. The “10-day observation method” is suitable for observation of animals or domestic pets, and requires ensuring that the injured animal is accessible for observation. Studies have shown that when rabies virus is contagious in an injured animal such as a cat or dog, a large number of rabies viruses have multiplied in the brain and within a few days, as the virus multiplies in the brain, morbidity and mortality will occur, usually with abnormal conditions, including anorexia, fever, difficulty swallowing, restlessness, easily frightened, and possibly aggressive behavior, and finally death. Post-exposure vaccination can be terminated if the injured animal is found to remain healthy for ten days during the observation period by the ten-day observation method, or if the animal is rabies-negative by professional laboratory testing. However, if the risk of disease cannot be ruled out by observing the animal, laboratory tests can also be performed to detect antibodies in the human body, which are usually less likely to develop the disease if they are high. Although the above methods can help rule out rabies, they are not absolute, so it is recommended that the entire post-exposure vaccination for rabies be administered, which is relatively safer.