Overall. There are two types of gallbladder removal and gallstone preservation. The former has a long history, indeed. As early as 1882, the famous German doctor Langenbuch performed the first cholecystectomy in Europe and proposed principles for the treatment of gallbladder stones. Its proposed warm-bed doctrine has become the gold standard of treatment for more than 100 years. The most important feature of cholecystectomy is the preservation of the gallbladder. It began in the 1880s. Because the gallbladder cavity could not be viewed directly, stones were often not removed without removing the gallbladder, resulting in recurrence of stones. Nowadays, with the development of endoscopic technology, biliary stone extraction has also gained good results and is gradually becoming an important treatment alternative to gallbladder removal for stone treatment. What are the effects of gallbladder removal on human body? 1. Indigestion, bloating and diarrhea. As far as is known, the gallbladder has at least the function of storage, concentration and contraction. It also has, of course, complex chemical and immune functions. Bile is secreted by hepatocytes through the capillary bile ducts, small bile ducts, left and right bile ducts, common hepatic ducts, along the cystic duct, and into the gallbladder for storage and concentration. The concentrated bile is 30 times more concentrated than hepatic bile and is reserved for high-fat meals before being discharged into the intestine to participate in digestion. If the gallbladder has been removed, here the liver bile from the liver discharge can not be stored, regardless of whether the human body needs, have to be continuously discharged into the intestine; to go to a banquet to eat sorghum thick taste, a lot of bile to help digestion, but at this time the body has no “surplus bile” to help, the symptoms of indigestion. 2.Gastric reflux of duodenal fluid after cholecystectomy, reflux of gastric fluid esophagus. In recent years, there have been many reports on Duodenogastric Reflux DGR and gastric reflux after cholecystectomy, and Walsh et al. also confirmed in a controlled study that all markers were refluxed to the gastroesophagus after cholecystectomy, accompanied by a significant decrease in the tone of the lower esophageal sphincter; Chen MF et al. The loss of bile reserve function causes bile to change from intermittent and feeding-related excretion to continuous excretion into the duodenum, at which time the chance of reflux into the stomach increases, producing DGR. leading to bile reflux gastritis or esophagitis, which brings a lot of pain to the patient. 3. The effect of cholecystectomy on the incidence of colon cancer. In recent years, many European scholars found a phenomenon and doubt, that is, among cases of colon cancer, many cases were found to have a history of cholecystectomy. In Moorehead’s analysis of 100 cases of cholecystectomy over 60 years old, 12 cases of colon cancer were found; while in another 100 cases without cholecystectomy, only 3 cases of colon cancer were found. 4, In addition, gallbladder resection is very easy to cause bile duct injury, some people count 500,000 cases of gallbladder resection each year, if calculated according to the lower chance of common bile duct injury 0.5%, there will be 2500 cases of common bile duct injury in China each year, if it happens to you, that is 100% reality.