A gallbladder neoplasm refers to an echogenic mass in the lumen of the gallbladder. A gallbladder neoplasm is a moderately echogenic mass that protrudes from the wall of the gallbladder into the fluid lumen of the gallbladder, is mulberry or polyp-like, has no acoustic shadow, and does not move with changes in body position. The diagnosis of gallbladder neoplasm is confirmed by the presence of these conditions. Neoplasm of the gallbladder usually refers to polyps or cholesterol crystals of the gallbladder, which usually have no obvious symptoms, but if it is combined with cholecystitis or gallbladder stones, it may present with pain in the right upper abdomen, nausea, vomiting, anorexia, etc. The condition should be treated with cholecystolithiasis. This condition should be differentiated from gallbladder stones. Single or a few stones, which move downward due to gravity when the body position changes, can be seen to move within the gallbladder, which can be used to help identify gallbladder neoplasm. If neoplasm is found in the gallbladder, it is important to consult a doctor to determine the condition and then standardize the treatment.