Side effects of glutamine include nausea, vomiting, and stomach upset. Vitamin B1 generally has no side effects, and overdose can cause allergic reactions, fatigue, and other discomforts. Glutathione can play the effect of sedation to help sleep, the indications for the use of the drug include neurosis, premenstrual tension syndrome and menopausal syndrome need to be sedated to help sleep. The contraindications for the use of the drug are not clear, the side effects of the drug include nausea, vomiting, stomach discomfort, rash, hair loss, dry mouth, fatigue, etc., usually after stopping the drug, the above side effects can disappear. Vitamin B1 is available in tablets and injections, and is indicated for the prevention and treatment of vitamin B1 deficiencies such as beriberi, neuritis, dyspepsia, and other vitamin B1 deficiencies. Contraindications to use include hypersensitivity to the product. Side effects do not usually occur at the recommended dose. In case of overdose of tablets, side effects such as headache, lack of appetite, diarrhea, fatigue, irritability, and swelling may occur; and the use of injections for intramuscular injection in large doses may cause allergic reactions (difficulty in swallowing, swelling of the face, lips, and eyelids, itching of the skin, wheezing, etc.). The specific use of drugs should be carried out under the guidance of a specialist, not unauthorized use of drugs.