At present, many rheumatic immune patients mention a common problem: “I want to come for follow-up, and I want to check some items beforehand, so what items are checked?” 1, the purpose of regular review Rheumatic immune disease is a chronic disease, requiring long-term use of some drugs with certain side effects. During the treatment process, doctors and patients need to be concerned about two major issues: Is the disease still active? Is there any toxicity of the medication taken? Therefore, corresponding examinations are needed according to these two major issues in order to adjust the treatment plan. 2, regular routine review items No matter which rheumatic immune disease, as long as a certain side effect of the drugs taken, should be reviewed items are routine blood, urine routine, liver function and kidney function, to understand the basic toxicity of drugs. The interval between blood and urine routine review is slightly shorter, while the interval between liver and kidney function review is slightly longer. Since most of the drug toxicity appears in the early stage of drug use, the review interval is shorter in the early stage of drug use, such as blood and urine routine can be 1-2 weeks, and if no side effects are found, the interval can be gradually extended from once every 2-4 weeks, once every 1-2 months, once every 2-3 months to once every 3-6 months, with the longest period not exceeding 6 months. Remember, any uncomfortable symptoms need to be reviewed by a doctor at any time. If there are multiple oral mucosal ulcers, you need to review the blood routine immediately, and greasy oil and unthinking diet need to review the liver function. 3, according to different rheumatic immune disease review different items Each rheumatic immune disease disease activity indicators are different, such as inflammatory arthritis including rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and reactive arthritis, etc., the main indicators to understand the disease activity is the blood sedimentation, C-reactive protein and joint Doppler ultrasound. Rheumatoid factor and anti-CCP antibodies are also useful in patients with rheumatoid arthritis, but they do not necessarily parallel the disease activity. In ankylosing spondylitis, HLA-B27 is not very meaningful because it is a genetic marker and has little relationship with disease activity. The main indicators of lupus disease activity are total complement, complement C3, C4, anti-ds-DNA antibody, anti-nucleosome antibody, urine routine and blood routine. The indicators of disease activity in patients with dermatomyositis and polymyositis are mainly the decrease of muscle enzymes in addition to the routine check of muscle strength. Patients with embolism and antiphospholipid syndrome should be checked for the combination of embolism, platelet aggregation rate, D-dimer, lupus anticoagulant, coagulation trio, anti-cardiolipin antibody and anti-β2-glycoprotein I antibody. The above disease activity indicators need to be checked once a month or several months according to the improvement or deterioration of symptoms. 4, according to the different drugs used to review different items rheumatologic immune diseases use different drugs, side effects also differ, in order to monitor the adverse drug reactions, in addition to the need to regularly check the above-mentioned blood and urine routine and liver and kidney function, but also need to carry out other corresponding checks. For example, patients with rheumatologic diseases who have been taking hormones for a long time should have their blood pressure, blood lipids, blood sugar, electrolytes and bone density checked at least once a few months. Long-term leflunomide users should have their blood pressure and chest X-ray checked at least once every few months. Long-term users of hydroxychloroquine should have their electrocardiogram and fundus checked once a year. Patients taking NSAIDs (Fotarolimus, Fenbendazole, Lapsone, Mupirocort, Acomplia, Nabumetone, Anti-inflammatory pain, etc.) need to have their stool routine and occult blood checked at least once every 1-2 weeks. In addition to stool routine and occult blood once every 1-2 weeks, platelet aggregation rate should be checked once a month for low-dose aspirin.