It is also usually feasible to switch to DPT vaccine after a polio dose has been administered. If you need to switch to DPT5 after the first dose of polio vaccine, there is no conflict in theory and there is no need to mind an additional dose of polio vaccine, which is harmless. The routine vaccination of DPT5 requires four doses, i.e. three doses for basic immunization at 2, 3 and 4 months of age or at 3, 4 and 5 months of age with an interval of 4 weeks each time, and the last booster dose for booster immunization at the 18th month, with an interval of at least 6 months between the booster and the third dose. Polio vaccination is the most cost-effective way to prevent and control the spread of polio, as it is effective in preventing and eliminating polio. And vaccination with DPT5 vaccine can prevent five diseases at the same time, including diphtheria, pertussis, tetanus, meningitis caused by Haemophilus influenzae type B, pneumonia, pericarditis, bacteremia, epiglottitis and poliomyelitis, which has high clinical significance. Before vaccination, parents should understand the vaccine species, effects, contraindications, adverse reactions, precautions, and costs to be borne, and truthfully provide the health condition of the baby and contraindications to vaccination to the health care personnel. After the vaccination, the baby should be observed at the vaccination site for 30 minutes and should not leave until there are no special conditions; individual babies may have reactions such as transient fever, redness, swelling, hard nodes and pain at the vaccination site after the vaccination, which generally do not require special treatment and can be relieved by themselves; if there are adverse reactions listed in the vaccine instructions, the baby should go to the hospital for consultation and treatment in time and inform the vaccination unit of the situation.