Ureteral stone injection of progesterone is usually effective in about half an hour and can reduce pain. Progesterone belongs to antispasmodic drugs, progesterone has a relaxing, antispasmodic, dilation of the ureter and urethral smooth muscle effect, ureteral stones caused by obstruction, pain can be injected with progesterone to relieve the pain, usually about half an hour after the injection can be effective, ureteral stones can also be excreted through the particles of the drug and extracorporeal lithotripsy to help the discharge of the stones. Although ureteral stones are benign, they can cause severe pain and require prompt treatment, regular follow-ups to monitor the discharge of stones, dietary adjustments, appropriate exercise, and medication as prescribed by the doctor.