Gout with hand numbness, generally considered to be caused by gout, need to receive painkillers, colchicine, glucocorticoids, as well as uric acid-lowering drug therapy. 1. Painkillers: generally need to accept non-steroidal anti-inflammatory drug treatment, such as Erythroxib and Celecoxib, etc., the common adverse effects of these drugs, generally include, nausea, diarrhea, etc., need to pay attention to pregnant women and lactating women should be careful. 2. Colchicine: commonly used in acute attacks of gouty arthritis, common adverse reactions include abdominal pain, diarrhea, vomiting, and oliguria, etc., and is contraindicated in patients with hepatic or renal insufficiency. 3. Glucocorticosteroids: such as hydrocortisone, common adverse effects include infection, peptic ulcer, Cushing’s syndrome, etc., contraindicated in pregnancy and lactation. 4. Uric acid-lowering drugs: such as allopurinol, which helps to inhibit urine production; benzbromarone, which helps to promote uric acid excretion, common adverse reactions generally include nausea, vomiting and diarrhea, etc., breastfeeding and pregnancy is prohibited for women. It is recommended that patients with gout accompanied by hand numbness go to the hospital in a timely manner, under the guidance of the doctor’s treatment, do not self-medication.