Which is better, earthworm kinase enteric-coated capsules or aspirin, cannot be directly assessed, the two drugs have different mechanisms of action. Earth kinase enteric capsules are extracted from earthworms, a protein hydrolase complex, can play an inhibitory role in the body of platelets, can be used for ischemic cardiovascular and cerebrovascular disease treatment. Aspirin’s main role is to inhibit the role of cyclooxygenase, ultimately reducing the production of thromboxane A2 in the body, inhibiting the aggregation of platelets. Earth kinase enteric-coated capsules and aspirin have different mechanisms of action, the two drugs can not do a direct comparison of the role of platelet inhibition, can be used for the treatment of ischemic cardiovascular and cerebrovascular diseases. The main adverse reactions of aspirin are gastric pain, gastric distension, gastric hemorrhage, skin mucosal bleeding, dyspnea, angioneurotic edema, etc. It is contraindicated in patients with allergy to drug components, aspirin-related asthma, aspirin-related angioedema, and hemophilia. Adverse reactions of enterokinase enteric capsules include dizziness, nausea, rash, constipation, etc. It is contraindicated in patients with allergy to drug components, active bleeding. No matter what kind of drugs need to be used under the guidance of a professional physician, not unauthorized use of drugs.