Coughing while lying down may be caused by gastroesophageal reflux disease (GERD), lung infections, cough variant asthma, etc. The specific type of medication to be taken needs to be treated under the guidance of a doctor to address the cause of the illness. 1. Gastroesophageal reflux disease (GERD): Coughing while lying down may be caused by damage to the structure of the lower esophageal sphincter, resulting in coughing after lying down when the gastroduodenal contents come into the pharynx or mouth without nausea or exertion, which can be treated with drugs such as domperidone and omeprazole. 2. Lung infection: if the patient’s lungs are infected, and the position changes while lying down, so that the secretions in the airway flow, thus stimulating the airway to cause coughing, you can take azithromycin, cefixime and other drugs. 3. Cough variant asthma: in the inhalation of odor, cold air, pollen will cause coughing, coughing at night is heavier, can be accompanied by chest tightness, itchy throat, can be treated by the use of salmeterol ticarcoson inhalation powder aerosol and other drugs. Lying down on the cough can also be caused by other diseases, such as the symptoms are more serious or persistent non-relief, it is recommended that patients go to the hospital in a timely manner, under the guidance of the doctor’s medication, the patient needs to strictly comply with the doctor’s instructions to use medication, do not blindly use medication or unauthorized changes in the dose of medication, in order to avoid the adverse effects on the body.