Diarrhea four or five times a day, this situation has two aspects of the cause: First, the result of inflammatory infections, mostly caused by cold and flu, often accompanied by fever, nausea, vomiting symptoms. Second, irritable bowel syndrome, which is the result of repeated poor rest or relatively high stress, as well as frequent insomnia, worry and anxiety, leading to dysfunction of the vegetative nerves, thus causing endocrine disorders and eventually causing irritable bowel syndrome. The former is mostly caused by viral or bacterial infections, while the latter is mostly caused by endocrine disorders resulting in neurological disorders, which in turn cause digestive malfunctions. In general, the former needs to be treated with anti-inflammatory rehydration and symptomatic treatment, while the latter needs to regulate the function of the plant nerves, such as haloperidol melitrexin tablets, pivotal ammonium bromide tablets, and glutathione tablets. If repeated diarrhea is not relieved, it is better to improve the colonoscopy to further assist the diagnosis and treatment.