Progressive vitiligo should actively cooperate with the doctor’s treatment, specific treatment methods include local medication, physical therapy, systemic medication and so on. 1. local medication: you can choose to use topical glucocorticoid drugs such as halomethasone ointment, compound flumethasone ointment, etc., but also tacrolimus ointment, pimecrolimus ointment, etc.; can also be used externally with vitamin D3 derivatives such as carbotriol ointment. 2. Physical therapy: 308nm excimer laser or narrow-spectrum medium-wave ultraviolet light can be used for physical therapy. 3. systematic use of drugs: progressive vitiligo can be systematic use of glucocorticoids, such as oral prednisone, or injection of compound betamethasone injection. The above drugs should be used under the guidance of a specialist physician, it is recommended that the patient regular follow-up, under the guidance of the doctor standardized treatment.