Diagnosis and treatment of Alzheimer’s disease

  Alzheimer’s disease is a progressive brain degenerative disease with unknown causes. It often starts with memory impairment, followed by impaired language, orientation, thinking, calculation, and motor functions, and declining ability in daily living, eventually making it impossible to live independently. According to statistics, the prevalence of dementia is 3.0~4.0% among people over 60 years old and 4.0~5.0% among people over 65 years old, with an increasing trend with age. For patients with mild Alzheimer’s disease, medications can improve the symptoms of dementia or slow down the progression of dementia to some extent. Therefore, early diagnosis and early treatment are crucial. The onset of Alzheimer’s disease is insidious and not easily detected, and patients are often dismissed by their families in the early stages as a general “old fogey”. Memory loss due to Alzheimer’s disease is characterized by poor short-term memory, where the names of things that have just happened are quickly forgotten, but events from years ago are still fresh in the mind. Therefore, family members need to pay close attention to the phenomenon of “confusion” in the elderly, and once they notice the unusual phenomenon, they should seek medical attention in time to avoid delaying the best treatment period. If some of the following symptoms appear: unable to call the name of an acquaintance, forgetting everything, even boiling the kettle dry or burning the rice; unable to accurately determine the location of things; feeling overwhelmed by new tasks; emotional indifference and suspiciousness, poor judgment, loss of generalization ability, distracted, unable to do shopping or miscalculation, lost, etc., you should promptly bring the patient to the hospital for consultation, most likely suffering from Alzheimer’s disease. It should also be distinguished from dementia caused by vascular dementia, Parkinson’s disease dementia, Pick’s disease, endocrine metabolic disorders (such as hypothyroidism, vitamin deficiency), traumatic brain injury, CO poisoning, meningoencephalitis, brain tumor, hydrocephalus and other dementia syndromes.  The survey shows that nearly 50% of the families do not know that the elderly have Alzheimer’s disease and feel that it is normal to be “old and confused”, so there is no need to see a doctor and take medication, and only 2% of the families take the elderly for proper treatment. Alzheimer’s disease not only threatens the health and happiness of the elderly in their later years, but also brings a heavy economic and psychological burden to the family and society. Based on clinical symptoms, neuroimaging and neuropsychological scale tests, most patients can be diagnosed early by us. To date, there is no cure for Alzheimer’s disease. However, there are many medications that have good effects in improving memory capacity, cognitive function and delaying aging in patients with Alzheimer’s disease. We advocate strengthening psychological support and behavioral guidance for patients, encouraging appropriate activities and exercise, supplemented by memory and thinking training, etc., when necessary. Pay attention to nutritional intake and early treatment. With proper treatment and intervention, patients’ condition can be delayed and quality of life can be improved.