The DPT vaccine can be given as long as it is within the expiration date. Pentavalent vaccine is a combination of inactivated polio vaccine, Haemophilus influenzae type b (Hib) vaccine, and acellular DPT vaccine, which can replace polio vaccine and DPT vaccine. This vaccine can effectively prevent diphtheria, tetanus, pertussis, and Hib-induced pneumonia, meningitis, pericarditis, and epiglottitis. A common adverse reaction to Pentavalent vaccine is redness, swelling, heat and pain at the site of vaccination, nodules and other symptoms, and may cause fever, and it is not recommended for people who are allergic to Pentavalent vaccine or patients with acute illnesses. In addition, parents are advised to consult with a specialist before giving the DPT vaccine to their children.