In daily life, there are many patients who suffer from cranial defects due to various reasons, and they are worried about the hazards of cranial defects, such as whether they will be afraid of heat, and what harm they will do to the brain, etc. In this regard, it is a common concern among patients that cranial defects may be very harmful. For the common concerns of patients, cranial defects can be very harmful, not only to the brain may be harmed, but also in the whole body may show a series of uncomfortable symptoms, known as “cranial defect syndrome”. The harm of cranial defects lies in the destruction of the integrity of the skull, the closure of the cranial cavity and the stability of the intracranial environment, thus causing cerebrospinal fluid circulation and blood circulation disorders, affecting the normal operation of the nerve function and causing a series of neurological symptoms. Some patients may manifest as dizziness, headache, limb weakness, poor fine activities, weakened vision, emotional instability, irritability and so on. Therefore, patients with cranial defects should undergo cranial repair. Cranial repair is a common neurosurgical procedure. For cranial bone repair surgery, one is to choose the excellent performance of the repair material, and the second is to the surgical operation skills also have high requirements. At present, there is a new type of special polymer material – polyether ether ketone PEEK material, performance is very excellent. PEEK material is not thermal conductivity, the patient will not be afraid of heat and cold, in addition to the hardness, stiffness, strength, elasticity, histocompatibility, etc. with the autologous cranial bone, and has become the new cranial bone repair material. Trend. It can achieve the organic unity of anatomical integrity, perfect function and beautiful appearance, which has been recognized and praised by patients, and it is a better material for repairing cranial defects.